The effect of recombinant human epidermal growth factor on radiation dermatitis in rectal and anal cancer patients: a self-controlled study

Table 1 The association between clinical characteristics and radiation dermatitis on the control side

		Total	RD grade			RD area score
		Total	0-I	II-IV	P ^a	≤ 2	> 2	P ^a
Gender					0.050			0.081
	Male	111	83	28		71	40
	Female	82	51	31		48	34
Age (years)					0.019			0.037
	≤ 55	101	76	25		67	34
	> 55	92	58	34		52	40
Tumor distance from anal verge					0.002			< 0.001
	≤ 4	104	66	38		52	52
	> 4	89	68	21		67	22
Colostomy ^b					0.291			0.002
	+	33	24	9		28	5
	-	160	110	50		91	69
Biological effective dose (Gy)					< 0.001			< 0.001
	≤ 60	167	124	43		110	57
	> 60	26	10	16		9	17
Fractionated dose (Gy)					0.003			0.012
	≤ 2	174	126	48		111	63
	> 2	19	8	11		8	11
Chemotherapy					0.216			1.000
	5FU/Capecitabine	7	6	1		5	2
	FOLFOX	171	120	51		101	70
	XELOX	4	4	0		3	1
	MMC + 5FU	11	4	7		4	7

ISSN: 1471-2407