Fig. 1From: Quantifying substantial carcinogenesis of genetic and environmental factors from measurement error in the number of stem cell divisionsDiagram of relationships between EH, LSCD0, LSCD, and LCR. The dotted node represents the unobserved variable, and the solid node represents observed variable. EH: a single variable denoting all the genetic and environmental factors that do not exist in the laboratory environment; LSCD: the true total number of divisions of all stem cells within this tissue per lifetime (from birth to age 74); LSCD0: the error-prone value of LSCD calculated using parameters estimated based on results of cell culture from mouse or human tissues in the laboratory environment; LCR: the observed lifetime cancer riskBack to article page