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Fig. 2 | BMC Cancer

Fig. 2

From: A nomogram combining clinical factors and biomarkers for predicting the recurrence of high-risk cutaneous squamous cell carcinoma

Fig. 2

Expression pattern of biomarkers in the cSCC tissue samples. Each column shows high (i), low (ii), and negative (iii) expression. Each row shows the expression patterns of different biomarkers. p53, p21, ARID1A, and ARID1B showed nuclear expression pattern in cSCC cells, and p16 and SNAIL showed expression in both the nucleus and cytoplasm. Axin2, CTTN, pTyr421-CTTN, pTyr466-CTTN, and MAGEA12, showed cytoplasmic expression (original magnification: × 200, scale bar: 100 μm; magnification for inset micrograph: × 1000, scale bar: 20 μm). ARID: AT-rich interaction domain; Axin2: axis inhibition protein 2; cSCC: cutaneous squamous cell carcinoma; MAGEA12: melanoma-associated antigen A12

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