Exosomal lncRNA HOTAIR induce macrophages to M2 polarization via PI3K/ p-AKT /AKT pathway and promote EMT and metastasis in laryngeal squamous cell carcinoma

Table 1 Relationship between CD163 and CD206 expression and clinicopathological parameters of 104 LSCC patients

Characteristic	N	CD163	P	CD206	P
Sex
Men	76	0.0521 ± 0.0323	0.3078	0.0464 ± 0.0317	0.5827
Women	28	0.0623 ± 0.0482		0.0519 ± 0.0492
Age(y)
< 58	62	0.0532 ± 0.0346	0.5935	0.0489 ± 0.0346	0.7370
≥ 58	42	0.0573 ± 0.0412		0.0463 ± 0.0408
Locations
Glottis	56	0.0496 ± 0.0204	0.1961	0.0422 ± 0.0118	0.0757
Supraglottis	40	0.0547 ± 0.0162		0.0483 ± 0.0176
Subglottis	8	0.0605 ± 0.0198		0.0531 ± 0.0306
T classification
Tis	16	0.0457 ± 0.0213	0.0223*	0.0404 ± 0.0188	0.0362*
T1/T2	46	0.0496 ± 0.0170		0.0427 ± 0.0134
T3/T4	42	0.0579 ± 0.0159		0.0503 ± 0.0173
Lymph nodes
N0	84	0.0504 ± 0.0307	0.0233*	0.0435 ± 0.0294	0.0307*
N1-3	20	0.0605 ± 0.0123		0.0534 ± 0.0140
Grading
Well	42	0.0485 ± 0.0174	0.1913	0.0462 ± 0.0172	0.4450
Moderately	34	0.0553 ± 0.0171		0.0471 ± 0.0158
Poorly	28	0.0546 ± 0.0188		0.0421 ± 0.0159
Pathological stage
0, I, II	62	0.0486 ± 0.0181	0.0065*	0.0421 ± 0.0149	0.0142*
III, IV	42	0.0579 ± 0.0159		0.0503 ± 0.0173

Relationship between the expression of CD163 and CD206 and clinicopathological parameters of 104 LSCC patients. Pathological staging was according to The International American Joint Committee on Cancer (AJCC-8). The “*” symbol indicates a statistically significant difference

ISSN: 1471-2407