Fig. 1
From: Tertiary lymphoid structures associate with improved survival in early oral tongue cancer
Invasive front and peritumoral areas in early oral tongue squamous cell carcinoma. A No observable tertiary lymphoid structures (TLSs). B Well-defined lymphoid follicles which can be likened to primary follicles. C Two peritumoral secondary lymphoid follicles at the invasive front of a tumor that is otherwise devoid of strong lymphocytic response. One of the aggregates with a germinal center is indicated with arrows with a second smaller one close by