EIF4A3-induced circBRWD3 promotes tumorigenesis of breast cancer through miR-142-3p_miR-142-5p/RAC1/PAK1 signaling

Table 1 The clinical characteristics of the studied BC patients

Variable	Number	circBRWD3 expression		P value
		Low (33)	High (33)
Age
< 40	32	17	15	0.622
≥ 40	34	16	18
Tumor size (cm)
< 2	36	25	11	0.012*
≥ 2	30	8	22
Lymph node metastasis
No	32	20	12	0.049*
Yes	34	13	21
TNM stage
I + II	28	18	10	0.046*
III + VI	38	15	23
Distant metastasis
No	30	20	10	0.013*
Yes	36	13	23
BMI
18.5–24	32	18	14	0.325
< 18.5	34	15	19
Smoking
No	40	19	21	0.614
Yes	26	14	12

ISSN: 1471-2407