Table 5 Safety and treatment exposure according to age
Parameter | < 70 years (n = 41) | ≥ 70 years (n = 10) |
|---|---|---|
Any grade TEAE | 35 (85%) | 9 (90%) |
Grade ≥ 3 TEAE | 14 (34%) | 5 (50%) |
Dose interruptions * | ||
Yes | 23 (56%) | 7 (78%) |
No | 18 (44%) | 2 (22%) |
Dose reduction * | ||
Yes | 18 (44%) | 7 (78%) |
No | 23 (56%) | 2 (22%) |
Reason for discontinuation | ||
Progression | 32 (78%) | 6 (60%) |
Toxicity | 3 (7%) | 2 (20%) |
Others† | 3 (7%) | 0 |
On treatment | 3 (7%) | 2 (20%) |