Table 1 Liver pathology evaluated by the nonalcoholic fatty liver disease activity score [20, 21]
From: Obese mammary tumour-bearing mice are highly sensitive to doxorubicin-induced hepatotoxicity
Components of nonalcoholic fatty liver disease activity score | ||
|---|---|---|
Item | Definition | Score |
Steatosis |  < 5% | 0 |
5%—33% | 1 | |
 > 33%—66% | 2 | |
 > 66% | 3 | |
Lobular inflammation | No foci | 0 |
 < 2 foci per 200 × field | 1 | |
2–4 foci per 200 × field | 2 | |
 > 4 foci per 200 × field | 3 | |
Ballooning | None | 0 |
Few balloon cells | 1 | |
Many cells/ prominent ballooning | 2 | |