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Fig. 5 | BMC Cancer

Fig. 5

From: Obese mammary tumour-bearing mice are highly sensitive to doxorubicin-induced hepatotoxicity

Fig. 5

Examples of pathological lesions observed in H&E-stained hepatic tissue in mice fed a HFD evaluated by the non-alcoholic fatty liver disease activity scoring system (NAS) (n = 4–5). Microvesicular steatosis (indicated by black arrows) and macrovesicular fatty infiltration in hepatocyte (steatosis) (indicated by red arrows), mild inflammation (inflammatory foci) (indicated by white arrows) and sinusoidal dilation (indicated by yellow arrow) within hepatocytes between the different groups. Images were taken at 20 × magnification, scale bar = 100 μm

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