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Table 3 Correlation of FAM99A expression with clinicopathologic features of patients in our HCC cohort.

From: Liver-specific lncRNA FAM99A may be a tumor suppressor and promising prognostic biomarker in hepatocellular carcinoma

Clinicopathological features

N

FAM99A expression

χ2

P

Low expression

High expression

Age (years)

   

1.033

0.309

 ≤ 50

30

13

17

  

 > 50

32

18

14

  

Gender

   

0.000

1.000

 Male

52

26

26

  

 Female

10

5

5

  

Liver cirrhosis

   

0.295

0.587

 Negative

20

11

9

  

 Positive

42

20

22

  

Hepatitis B virus infection

   

0.144

0.705

 Negative

8

3

5

  

 Positive

54

28

26

  

AFP level (ng/ml)

   

1.033

0.309

 ≤ 400

32

18

14

  

 > 400

30

13

17

  

Tumor size (cm)

   

3.161

0.075

 < 7

31

12

19

  

 ≥ 7

31

19

12

  

Tumor number

   

0.477

0.490

 Single

52

25

27

  

 Multiple

10

6

4

  

Microvascular invasion

   

4.168

0.041

 Negative

28

10

18

  

 Positive

34

21

13

  

Lymph nodes metastasis

   

0.000

1.000

 Negative

58

29

29

  

 Positive

4

2

2

  

Edmondson-Steiner grade

   

0.265

0.607

 I-II

26

12

14

  

 III-IV

36

19

17

  

BCLC stage

   

4.633

0.099

 A stage

31

12

19

  

 B stage

12

9

3

  

 C stage

19

10

9

  

Child-Pugh classification grade

   

0.000

1.000

 A

57

28

29

  

 B

5

3

2

  
  1. Statistically significant P values are in bold (P < 0.05)
  2. HCC hepatocellular carcinoma; AFP alpha-fetoprotein; BCLC Barcelona Clinic Liver Cancer