Skip to main content

Table 2 The association of clinicopathological and immunological characteristics with 5-year recurrence

From: CD4 and FOXP3 as predictive markers for the recurrence of T3/T4a stage II colorectal cancer: applying a novel discrete Bayes decision rule

Variables

n = 137

5-year recurrence: Yes (n = 34)

5-year recurrence: No (n = 103)

Age♦

73.0 [63.5, 78.8]

70.0 [61.5, 77.0]

Sex: male/female

18/16

55/48

T factor: T3/T4a

28/6

88/15

Histologic grade

 well

5

20

 moderately

26

78

 poorly

1

2

 mucinous

0

2

 undifferentiated

2

1

Vascular/lymphatic invasion: present/absent

21/13

49/54

Location: left side/right side

19/15

62/41

Perforation: present/absent

0/34

2/101

Adjuvant therapy: Yes/No

24/10

63/40

CD3 density: High/Low

13/21

47/56

CD4 density: High/Low

8/26

57/46

CD8 density: High/Low

13/21

54/49

FOXP3 density: High/Low

6/28

43/60

CD4 & FOXP3 densities: Low & Low/Other combinations

23/11

32/71

  1. ♦median [interquartile range]; high values of CD3, CD8, CD4 nad FOXP3 are ≥ 339.1, ≥ 72.2, ≥ 64.6 and ≥ 89.1 cells/mm2, respectively