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Table 5 The relationship between the expression of IDO2 in MTC tissues/corresponding lymph node tissues, lymph node metastasis, and CD4 + T cell infiltrations

From: Indoleamine 2,3-dioxygenase 2 immunohistochemical expression in medullary thyroid carcinoma: implications in prognosis and immunomodulatory effects

 

Total

N (%)

Spearman’s r

P

  

LN high expression

LN low expression

0.227

0.002 *

With LN metastasis

100(53.5)

46(46.0)

54(54.0)

  

Without LN metastasis

87(46.5)

21(24.1)

66(75.9)

  
  

LN high expression

LN low expression

0.268

0.022 *

Tissue high expression

77(41.2)

35(45.5)

42(54.5)

  

Tissue low expression

110(58.8)

32(29.1)

78(70.9)

  
  

Tissue high expression

Tissue low expression

-0.243

0.001*

CD4 low

87(6.5)

47(54.0)

40(46.0)

  

CD4 high

100(53.5)

30(30.0)

70(70.0)

  
  1. *P<0.05; MTC, medullary thyroid carcinoma; IDO2, indoleamine 2,3-dioxygenase 2