Fig. 6
From: NOVA1 promotes NSCLC proliferation and invasion by activating Wnt/β-catenin signaling
Overexpression of β-catenin can reverse the inhibitory effects of siNOVA1 in lung cancer cells. A The mRNA levels of β-catenin in A549 and H1299 cells transfected with siRNA negative siNC and siNOVA1#1, **P < 0 .01. B The protein levels of β-catenin and activity of β-catenin in A549 and H1299 cells transfected with siNC and siNOVA1#1. C The protein levels of β-catenin in A549 and H1299 cells transfected with β-catenin plasmid. D The growth curves of A549 and H1299 cells transfected with siNC, siNOVA1#1 and siNOVA1 + β-catenin plasmid. E The invasion of A549 and H1299 cells transfected with siNC, siNOVA1#1 and siNOVA1 + β-catenin plasmid, **P < 0 .01; ***P < 0 .001