Fig. 9

Oncogenic function of TNFAIP2 in AML cells. a qRT-PCR was performed to examine the efficiency of TNFAIP2 silencing in short hairpin RNA-stably transduced AML cell lines THP-1 and U937 at 120-hour post-transfection. b, c Cellular proliferation upon silencing of TNFAIP2 in THP-1 (b) and U937 (c) cells was studied by CCK-8 assay after transfection. d, e The cell-cycle distribution upon silencing of TNFAIP2 in THP-1 (d) and U937 (e) cells was studied by flow cytometry at 120-hour post-transfection. f, g The cell apoptosis upon silencing of TNFAIP2 in THP-1 (f) and U937 (g) cells was studied by flow cytometry at 120-hour post-transfection. Columns represented mean +/− 1SD from three independent experiments