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Table 1 Univariate analysis of preoperative factors and surgery affecting cancer-specific and overall survival

From: Surgical efficacy and survival prediction of patients with unspecified malignant bone tumors

Factors

Cancer-specific survival

Overall survival

n

5-year Survival rate (%, mean ± SE)

p value

n

5-year Survival rate (%, mean ± SE)

p value

Age:18–66/> 66 yrs

201/91

56.1 ± 3.8/24.8 ± 5.2

< 0.001

254/146

46.5 ± 3.4/13.7 ± 3.0

< 0.001

Race: Black/white/othersa

37/235/13

56.5 ± 8.6/44.7 ± 3.6 /27.7 ± 15.0

0.532

48/323/23

45.7 ± 7.8/32.7 ± 2.7 /17.2 ± 8.9

0.408

Gender: Female/male

138/154

46.6 ± 4.5/46.7 ± 4.5

0.434

195/205

35.5 ± 3.6/33.3 ± 3.5

0.895

Diagnosis year: ≤2000/> 2000

77/215

53.0 ± 5.8/44.2 ± 3.9

0.048

94/306

43.6 ± 5.1/31.1 ± 2.9

0.011

Region: Southeast/pacific coast/ northern plains/east

28/118/ 28/118

23.6 ± 11.9/42.3 ± 5.2/ 36.3 ± 9.4/53.7 ± 4.9

0.533

34/176/ 38/152

32.5 ± 9.2/31.2 ± 3.8/ 25.2 ± 7.2/40.3 ± 4.1

0.516

Site: Limbs/spine/othersb

161/46/85

49.1 ± 4.3/67.3 ± 7.5 /31.2 ± 5.6

< 0.001

194/74/132

40.3 ± 3.7/48.5 ± 6.3 /17.8 ± 3.6

< 0.001

Tumor laterality: Left/right

111/95

51.6 ± 5.1/40.6 ± 5.6

0.145

139/139

41.2 ± 4.3/30.3 ± 4.2

0.070

Tumor extent: Localized/regional/distant

84/84/79

66.7 ± 5.5/52.4 ± 6.4 /8.5 ± 3.6

< 0.001

123/112/108

44.9 ± 4.7/41.6 ± 5.2 /6.3 ± 2.5

< 0.001

Tumor size: ≤105(108)/105(108) mm

116/23

57.6 ± 5.2/6.5 ± 6.0

< 0.001

167/29

44.0 ± 4.2/4.8 ± 4.5

< 0.001

Primary tumor surgery: Yes/no

164/128

57.7 ± 4.3/32.4 ± 4.4

< 0.001

213/187

46.7 ± 3.7/20.5 ± 3.1

< 0.001

Pathology grade: I/II/III/IV

12/21/39/100

82.5 ± 11.3/86.9 ± 8.7/ 36.7 ± 8.4/35.3 ± 5.3

< 0.001

14/34/55/137

84.4 ± 10.2/64.5 ± 9.3 /23.8 ± 6.1/27.8 ± 4.1

< 0.001

First tumor diagnosed: Yes/no

292/0

\

\

293/107

40.7 ± 3.0/16.7 ± 4.0

< 0.001

Annual income aggregate level: Low/High (Cutoff: 75,000USD)

162/130

43.5 ± 4.3/50.7 ± 4.7

0.185

210/190

32.4 ± 3.5/36.4 ± 3.6

0.338

Hispanic: Yes/no

43/249

42.2 ± 7.9/47.7 ± 3.5

0.422

52/348

40.0 ± 7.2/33.7 ± 2.7

0.516

Marital status: Single/married/othersc

135/66/68

48.1.1 ± 4.8/51.0 ± 6.6 /32.8 ± 6.1

< 0.001

191/82/97

34.2 ± 3.7/43.8 ± 5.8 /21.9 ± 4.4

< 0.001

  1. SE standard error, yrs years old, USD US dollar
  2. aincluding: American Indian/AK Native, Asian/Pacific Islander
  3. bincluding: mandible/skull, face and associated joints/rib, sternum, clavicle and associated joints
  4. cincluding: divorced, separated, widowed