Chemotherapy dose per kilogram lean body mass increased dose-limiting toxicity event in male head and neck cancer with taxane and platinum-based induction therapy

Table 2 Frequency of toxicity events after the first cycle of induction chemotherapy (n = 179)

Variables	Number	%
Grade III + hematological adverse events	35	19.5
Neutropenia	34	19
Anemia	2	1.1
Thrombocytopenia	0	0
Grade III + non-hematological adverse events	1	0.6
Acute liver injury	0	0
Acute kidney injury	1	0.6
Grade III + hematological and non-hematological adverse events	35	19.6
Subsequent chemotherapy dose reduction more than 50%	0	0
Postponement of chemotherapy > = 4 days	9	5
Death during or after chemotherapy	8	4.5
Overall DLT events	43	24

ISSN: 1471-2407