Table 1 Difference in patients’ characteristics between the ND alone group and ND + PAT group in the original observational and propensity-matched cohorts
Observational dataset (n = 342) | PSM dataset(n = 228) | |||||
|---|---|---|---|---|---|---|
Characteristic | ND | ND + PAT | P | ND | ND + PAT | P |
Total | 266 | 76 | 152 | 76 | ||
Age, y | 0.954 | 0.925 | ||||
< 45 | 141(53.0) | 40(52.6) | 81(53.3) | 40(52.6) | ||
≥ 45 | 125(47.0) | 36(47.4) | 71 (46.7) | 36(47.4) | ||
Gender | 0.159 | 0.724 | ||||
Female | 70(26.3) | 14(18.4) | 31(20.4) | 14(18.4) | ||
Male | 196(73.7) | 62(81.6) | 121(79.6) | 62(81.6) | ||
Status of lymph node | 0.036 | 0.120 | ||||
Recurrence | 201(75.6) | 66(86.8) | 119(78.3) | 66(86.8) | ||
Residual | 65(24.4) | 10(13.2) | 33(21.7) | 10(13.2) | ||
rN stage* | 0.002 | 0.538 | ||||
N1 | 205(77.1) | 46(60.5) | 102(68.9) | 46(60.5) | ||
N2 | 14(5.3) | 2(2.6) | 5(3.3) | 2(2.6) | ||
N3 | 47(17.7) | 28(36.8) | 45(29.6) | 28(36.8) | ||
Preoperative EBV DNA level | 0.072 | 0.554 | ||||
undetectable | 129(48.5) | 28(36.8) | 50(32.9) | 28(36.8) | ||
detectable | 137(51.5) | 48(63.2) | 102(67.1) | 48(63.2) | ||
PLNs | 0.002 | 0.261 | ||||
≤ 2 | 172(64.7) | 34(44.7) | 80(52.6) | 34(44.7) | ||
> 2 | 94(35.3) | 42(55.3) | 72(47.4) | 42(55.3) | ||
Maximal diameter of LNs (mm) | 0.555 | 0.651 | ||||
> 20 | 72(27.1) | 18(23.7) | 32(21.1) | 18(23.7) | ||
≤ 20 | 194(72.9) | 58(76.3) | 120(78.9) | 58(76.3) | ||
ECS | 0.007 | 0.399 | ||||
Yes | 91(34.2) | 39(51.3) | 69(45.4) | 39(51.3) | ||
No | 175(65.8) | 37(48.7) | 83(54.6) | 37(48.7) | ||
Bilaterality | 0.132 | 0.435 | ||||
Unilateral | 256(96.2) | 70(92.1) | 144(94.7) | 70(92.1) | ||
Bilateral | 10(3.8) | 6(7.9) | 8(5.3) | 6(7.9) | ||
Surgical methods | 0.616 | 1.000 | ||||
SND | 210(78.9) | 62(81.6) | 124(81.6) | 62(81.6) | ||
RND | 56(21.1) | 14(18.4) | 28(18.4) | 14(18.4) | ||
postoperative adjuvant therapy | NA | NA | ||||
Radiation | NA | 18 (23.7) | NA | 18 (23.7) | ||
Chemotherapy | NA | 44 (57.9) | NA | 44 (57.9) | ||
Chemoradiotherapy NA | 14 (18.4) | NA | 14 (18.4) | |||