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Table 2 Frequencies of CYP2D6 genotypes and predicted phenotypes according to AS

From: The frequencies of CYP2D6 alleles and their impact on clinical outcomes of adjuvant tamoxifen therapy in Syrian breast cancer patients

Phenotypes

Genotypes

AS

N (%)

NMs

(1 < AS ≤ 2.25)

*1/*1

2

22 (22.7)

*1/*2

2

37 (38.1)

*2/*2

2

1 (1)

*1/*41

1.5

14 (14.4)

*2/*41

1.5

3 (3.1)

*1/*10

1.25

1 (1)

*2/*10

1.25

1 (1)

IMs

(0 < AS ≤ 1)

*1/*4

1

3 (3.1)

*2/*4

1

1 (1)

*41/*10

0.75

1 (1)

*10/*10

0.5

2 (2.1)

*10/*4

0.25

4 (4.1)

*10/*69

0.25

3 (3.1)

PMs

(AS = 0)

*4/*4

0

2 (2.1)

*4/*69

0

2 (2.1)