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Table 2 Association between inflammatory burden index and overall survival of patients with patients with colorectal cancer

From: Lymphocyte to C-reactive protein ratio could better predict the prognosis of patients with stage IV cancer

Variables

Model a

Model b

Model c

 

HR (95%CI)

p value

HR (95%CI)

p value

HR (95%CI)

p value

LCR

 Continuous (per SD)

0.824 (0.759,0.895)

 < 0.001

0.837 (0.77,0.91)

 < 0.001

0.848 (0.781,0.922)

 < 0.001

 Cutoff value

 

 < 0.001

 

 < 0.001

 

 < 0.001

 C1 (< 2813.953)

ref

 

ref

 

ref

 

 C2 (≥ 2813.953)

0.551 (0.494,0.616)

 

0.589 (0.526,0.659)

 < 0.001

0.605 (0.54,0.678)

 

Quartiles

 Q1 (< 4.08)

ref

 

ref

 

ref

 

 Q2 (4.08–11.37)

0.716 (0.622,0.825)

 < 0.001

0.726 (0.629,0.839)

 < 0.001

0.744 (0.644,0.86)

 < 0.001

 Q3 (11.37–65.47)

0.548 (0.473,0.635)

 < 0.001

0.581 (0.5,0.675)

 < 0.001

0.605 (0.52,0.704)

 < 0.001

 Q4 (≥ 65.47)

0.437 (0.376,0.508)

 < 0.001

0.48 (0.412,0.559)

 < 0.001

0.502 (0.43,0.585)

 < 0.001

 p for trend

 

 < 0.001

 

 < 0.001

 

 < 0.001

  1. Model a: No adjusted
  2. Model b: Adjusted for age, sex, BMI, TNM stage
  3. Model c: Adjusted for age, sex, BMI, TNM stage, tumor type, surgery, radiotherapy, chemotherapy, hypertension, diabetes, smoking, drinking, family history
  4. HR Hazard ratio, 95%CI 95%confidence intervals, NLR Neutrophil-to-lymphocyte ratio