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Table 1 Characteristics of 45,380 participants stratified by sex

From: Modifiable lifestyle factors have a larger contribution to colorectal neoplasms than family history

 

Total (n = 45,380)

Male (n = 21,415)

Female (n = 23,965)

Age at colonoscopy, years (%)

  < 50

2896 (6.4)

1469 (6.9)

1427 (6.0)

 50–60

11,597 (25.6)

5054 (23.6)

6543 (27.3)

 60–70

21,403 (47.2)

10,010 (46.7)

11,393 (47.5)

  ≥ 70

9484 (20.9)

4882 (22.8)

4602 (19.2)

Educational level (%)

 Low

9166 (20.2)

3784 (17.7)

5382 (22.5)

 Intermediate

30,013 (66.1)

14,224 (66.4)

15,789 (65.9)

 High

6201 (13.7)

3407 (15.9)

2794 (11.7)

Marital status (%)

 Married

43,468 (95.8)

20,814 (97.2)

22,654 (94.5)

 Unmarried

429 (0.9)

218 (1.0)

211 (0.9)

 Divorced

343 (0.8)

128 (0.6)

215 (0.9)

 Widowed

1140 (2.5)

255 (1.2)

885 (3.7)

Smoking status (%)

 Never

35,007 (77.1)

12,703 (59.3)

22,304 (93.1)

 Former

1928 (4.2)

1640 (7.7)

288 (1.2)

 Current

8445 (18.6)

7072 (33.0)

1373 (5.7)

  Cigarettes per day, mean (SD)

16.01 (9.30)

16.38 (9.51)

14.06 (7.81)

Alcohol consumption (%)

 Never drinker

40,699 (89.7)

16,915 (79.0)

23,784 (99.2)

 Ever drinker

4681 (10.3)

4500 (21.0)

181 (0.8)

  Alcohol (g) consumed per dayb, mean (SD)

38.98 (28.53)

39.24 (24.77)

31.53 (80.85)

Physical activity (%)

 Physical inactivity

25,411 (56.0)

11,636 (54.3)

13,775 (57.5)

 Regular activity

19,969 (44.0)

9779 (45.7)

10,190 (42.5)

BMI, kg/m2 (%)

  < 25

26,124 (57.6)

11,865 (55.4)

14,259 (59.5)

 25–29.9

16,414 (36.2)

8319 (38.8)

8095 (33.8)

  ≥ 30

2842 (6.3)

1231 (5.7)

1611 (6.7)

Colonoscopy findings (%)

 Normal

24,176 (53.3)

9501 (44.4)

14,675 (61.2)

 Nonadvanced CRN

17,823 (39.3)

9788 (45.7)

8035 (33.5)

 Advanced CRN

3381 (7.5)

2126 (9.9)

1255 (5.2)

  Advanced adenoma

2688 (79.5)

1714 (80.6)

974 (77.6)

  CRC

693 (20.5)

412 (19.4)

281 (22.4)

Family history of CRC in FDR (%)

 No

41,820 (92.2)

19,863 (92.8)

21,957 (91.6)

 Yes

3560 (7.8)

1552 (7.2)

2008 (8.4)

Tumor locationa (%)

 Colon

14,524 (68.5)

7964 (66.8)

6560 (70.6)

 Rectum

2867 (13.5)

1494 (12.5)

1373 (14.8)

 Unspecific

3813 (18.0)

2456 (20.6)

1357 (14.6)

  1. CRN Colorectal neoplasm, BMI Body mass index, CRC Colorectal cancer, FDR First-degree relative
  2. a The distribution of tumor location was based on 21,204 participants who diagnosed with colorectal neoplasms
  3. b The amount of consumed alcohol was calculated based on a common type of Chinese spirits (38°), which contains about 17.1 g alcohol in one unit (50 g spirits)