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Fig. 5 | BMC Cancer

Fig. 5

From: Adjuvant effect of IRES-based single-stranded RNA on melanoma immunotherapy

Fig. 5

CrPVIRES-ssRNA reduces tumor burden in mouse melanoma. Mice (C57BL/6) were challenged with a subcutaneous injection of B16-Ova cells (5 × 10.5 cells) on day 0. Then, the mice were immunized intramuscularly with Ova protein (50 μg), poly(I:C) (20 μg) and CrPVIRES-ssRNA (20 μg) every 2 days until day 7. A Representative tumor images harvested on day 31. B Tumor size was measured every 2 days in the indicated groups. C Weight of tumors harvested on day 31. D Mice weights were measured every 2 days. Data were represented as mean ± SD. Statistical significance was indicated by *p < 0.05 and **p < 0.01

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