Table 1 Comparison of patient characteristics between non- and hepatocellular carcinoma (HCC) patient groups
Characteristics | Non-HCC | HCC | p value | ||
|---|---|---|---|---|---|
Healthy | Chronic hepatitis | Liver Cirrhosis | |||
Gender, male/female (n) | 5/15 | 4/14 | 8/29 | 67/10 | < 0.001 |
Age (years) | 66.5 (48.3–75.8) | 43.0 (31.5–50.5) | 51.0 (42.0-65.5) | 55.0 (47.5–67.0) | < 0.001 |
ALT (U/L) | 17.3 (10.0–26.7) | 132.5 (82.8-345.5) | 37.4 (26.6–65.4) | 31.0 (20.0-53.3) | < 0.001 |
AST (U/L) | 25.4 (20.8–31.1) | 70.3 (31.8–177.0) | 45.9 (34.6–87.3) | 42.5 (27.5–89.7) | < 0.001 |
TBIL (µmol/L) | 15.3 (12.4–18.4) | 78.5 (50.0-125.7) | 25.4 (17.5–56.3) | 20.4 (13.1–48.2) | < 0.001 |
ALB (g/L) | 44.5 (43.0-45.8) | 34.4 (29.6–35.0) | 36.3 (30.3–61.9) | 34.1 (28.1–37.4) | < 0.001 |
RBG (mmol/L) | 5.23 (4.97–5.44) | 4.64 (4.11–5.43) | 4.81 (4.28–6.05) | 4.80 (4.26–5.96) | < 0.001 |
TC (mmol/L) | 5.26 (3.92–6.08) | 3.65 (2.96–4.30) | 3.42 (2.59–3.74) | 3.89 (3.13–4.54) | < 0.001 |
TG (mmol/L) | 0.98 (0.73–1.36) | 0.87 (0.55–1.32) | 0.61 (0.44–0.98) | 0.88 (0.59–1.26) | 0.002 |
PT (seconds) | NA | 14.30 (12.30-16.45) | 15.95 (14.30-17.48) | 13.05 (11.90-15.15) | < 0.001 |
WBC count (×109/L) | 5.39 (4.82–6.63) | 5.45 (3.22–7.29) | 3.73 (2.54–4.73) | 4.45 (2.97–5.94) | 0.007 |
Platelet count (×109/L) | 234.0 (196.5-289.8) | 172.0 (114.5-232.3) | 67.0 (51.0-99.5) | 91.0 (63.0-150.0) | < 0.001 |
AFP (ng/mL) | 2.39 (1.77–3.95) | 407.95 (84.90-817.35) | 5.99 (2.05–44.82) | 22.72 (2.92–608.70) | < 0.001 |
CEA (ng/mL) | 1.88 (0.98–2.77) | 3.08 (1.82–5.87) | 2.67 (1.64–4.60) | 2.93 (2.00-4.79) | 0.011 |
AAR | 1.44 (1.03–2.15) | 0.58 (0.35–0.94) | 1.35 (1.07–1.64) | 1.40 (1.03–1.93) | < 0.001 |
G-Test | 3.04 (1.54-4.00) | 3.64 (2.77–5.12) | 3.85 (2.59–6.03) | 6.53 (5.87–7.38) | < 0.001 |