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Table 2 Correlation between plasma circN4BP2L2 expression level and clinicopathologic parameters of EOC (n = 180)

From: Diagnostic value of circN4BP2L2 in type I and type II epithelial ovarian cancer

Parameter

EOC (n = 180)

Type I EOC (n = 70)

Type II EOC (n = 110)

n (%)

CircN4BP2L2, Mean ± SD

p

n (%)

CircN4BP2L2, Mean ± SD

p

n (%)

CircN4BP2L2, Mean ± SD

p

Age

  

0.52

  

0.70

  

0.47

 ≤ 50y

54 (30%)

27.48 ± 21.15

 

17 (24%)

30.24 ± 24.74

 

37 (34%)

26.21 ± 19.52

 

 > 50y

126 (70%)

26.70 ± 22.51

 

53 (76%)

31.04 ± 24.92

 

73 (66%)

23.54 ± 20.19

 

Histology

  

0.75

  

0.11

  

0.76

 Serous

106 (59%)

27.01 ± 22.88

 

18 (26%)

40.11 ± 30.81

 

88 (80%)

28.53 ± 22.19

 

 Others

74 (41%)

26.81 ± 20.98

 

52 (74%)

27.64 ± 21.64

 

22 (20%)

23.30 ± 19.22

 

FIGO stage

  

< 0.01*

  

< 0.01*

  

0.44

 I + II

64 (36%)

35.19 ± 25.19

 

40 (57%)

39.19 ± 26.29

 

24 (22%)

39.19 ± 26.29

 

 III + IV

116 (64%)

22.38 ± 18.73

 

30 (43%)

19.73 ± 17.27

 

86 (78%)

19.73 ± 17.27

 

Grade

  

0.03*

  

0.15

  

NA

 G1

54 (30%)

32.69 ± 25.61

 

54 (77%)

32.69 ± 25.61

 

0 (0%)

NA

 

 G2 + G3

126 (70%)

24.47 ± 19.96

 

16 (23%)

24.64 ± 20.88

 

110 (100%)

24.44 ± 19.92

 

LNM a

  

< 0.01*

  

0.70

  

0.04*

 Yes

59 (40%)

19.71 ± 15.11

 

8 (14%)

19.27 ± 10.81

 

51 (57%)

19.78 ± 15.76

 

 No

89 (60%)

30.46 ± 23.00

 

50 (86%)

31.61 ± 24.55

 

39 (43%)

29.00 ± 21.07

 
  1. Notes: a The information for lymph node metastasis was only available in 148 EOC patients
  2. Abbreviations: n, number; FIGO, International Federation of Gynecology and Obstetrics; G, grade; LNM, lymph node metastasis; SD, standard deviation; NA, not available