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Table 3 The positive staining rates of CD31, VMI, HER2, TUNEL and E-cadherin in the four groups at the end of treatment

From: Evaluating the efficacy and microenvironment changes of HER2 + gastric cancer during HLX02 and Endostar treatment using quantitative MRI

Index

Group 1

Group 2

Group 3

Group 4

F

P

CD31 (%)

46.5 ± 4.2

25.8 ± 6.2

35.7 ± 3.1

18.6 ± 2.4

57.962

0.001

VMI (%)

30.9 ± 4.0

61.7 ± 5.6

45.7 ± 6.0

68.1 ± 6.2

64.051

0.001

HER2 (%)

72.1 ± 7.0

69.5 ± 8.4

37.4 ± 4.9

28.8 ± 4.7

83.141

0.001

TUNEL (%)

17.3 ± 5.2

39.8 ± 5.3

48.3 ± 5.7

84.4 ± 6.0

174.221

0.001

E-cadherin (%)

48.4 ± 5.9

68.6 ± 6.5

41.2 ± 4.6

80.2 ± 4.5

76.733

0.001

  1. The P-value was generated by one-way analysis of variance
  2. VMI Vessel maturity index, HER2 Human epidermal growth factor 2, TUNEL Terminal-deoxynucleoitidyl transferase mediated nick end labeling