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Table 2 The quantitative IVIM-DWI parameters at different time points from the four groups

From: Evaluating the efficacy and microenvironment changes of HER2 + gastric cancer during HLX02 and Endostar treatment using quantitative MRI

Parameter

Groups

Base

5d

10d

15d

20d

F

P

D

(10−3mm2/s)

Group 1

0.655 ± 0.031

0.643 ± 0.028

0.558 ± 0.035

0.581 ± 0.041

0.586 ± s0.040

9.705

0.001

Group 2

0.650 ± 0.022

0.626 ± 0.018

0.678 ± 0.032

0.680 ± 0.024

0.655 ± 0.023

5.768

0.001

Group 3

0.643 ± 0.030

0.660 ± 0.024

0.698 ± 0.023

0.727 ± 0.024

0.740 ± 0.043

13.717

0.001

Group 4

0.658 ± 0.025

0.677 ± 0.035

0.766 ± 0.028

0.855 ± 0.031

0.900 ± 0.035

83.484

0.001

D*

(10−3mm2/s)

Group 1

10.3 ± 0.9

11.7 ± 0.7

13.7 ± 0.7

14.2 ± 0.6

14.1 ± 0.5

42.501

0.001

Group 2

10.7 ± 0.5

13.4 ± 0.5

17.4 ± 0.9

15.9 ± 0.8

15.5 ± 0.5

104.402

0.001

Group 3

10.6 ± 0.4

11.3 ± 0.6

13.3 ± 0.6

13.0 ± 0.5

10.8 ± 0.4

42.051

0.001

Group 4

10.7 ± 0.6

12.3 ± 0.7

16.0 ± 0.4

14.8 ± 0.4

12.8 ± 0.6

105.389

0.001

f (%)

Group 1

20.4 ± 0.8

22.2 ± 1.0

23.6 ± 0.8

23.0 ± 0.9

24.7 ± 0.6

26.388

0.001

Group 2

20.9 ± 0.9

26.7 ± 0.8

29.5 ± 0.7

27.0 ± 0.9

25.4 ± 0.9

101.573

0.001

Group 3

21.0 ± 0.9

23.4 ± 0.8

25.0 ± 0.8

23.1 ± 0.9

22.4 ± 0.8

21.451

0.001

Group 4

20.9 ± 0.9

24.8 ± 0.8

26.8 ± 0.9

24.9 ± 1.2

23.6 ± 0.8

37.123

0.001

  1. The P-value was generated by one-way analysis of variance