Fig. 3

The potential molecular mechanism of acquiring a malignant phenotype of osteosarcoma cells by silencing LRIG2. All the blots were cut prior to hybridization with antibodies. A Western blot was used to analyze the apoptosis related protein (BAX, BCL2, caspase9 and caspase3) in OS cells transfected with sh-LRIG2 or NC. B Western blots of AKT, p-AKT in OS cells. C Western blots of N-cadherin, Vimentin in OS cells