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Fig. 7 | BMC Cancer

Fig. 7

From: Identification and validation of a fatty acid metabolism-related lncRNA signature as a predictor for prognosis and immunotherapy in patients with liver cancer

Fig. 7

Integrative Analysis of FA metabolism-related lncRNAs. A Correlation coefficient density curve of FA metabolism-related lncRNAs and PCG. B The cellular component of FA metabolism-associated lncRNAs in cell lines. RCI < 0 indicates nuclear localization and RCI > 0 indicates cytoplasmic localization. C The distribution of TFs has a significant negative correlation with nuclear lncRNAs in the two cohorts. D Locations of the 12 lncRNAs in the signature. E Distribution of the activated and suppressed TFs in C2 compared with C1 in the TCGA and GSE76427 cohorts. F The results of the functional enrichment analysis of TFs up-regulated in the C1 subtype. G The dysregulation in TF activity of the up-regulated transcription factors in the TCGA subtypes. Abbreviations: FA, Fatty acid; LncRNA, Long non-coding RNA; HCC, Hepatocellular carcinoma; TCGA, The Cancer Genome Atlas; PCG, Protein coding gene; RCI, relative concentration index; TF, Transcriptional factor

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