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Fig. 4 | BMC Cancer

Fig. 4

From: RAD6 inhibition enhances paclitaxel sensitivity of triple negative breast cancer cells by aggravating mitotic spindle damage

Fig. 4

Paclitaxel and SMI#9 decrease 1N3R TAU isoform and modulate cyclin B1 protein levels differently in paclitaxel-sensitive and intrinsically resistant TNBC cells. Western blot analysis of the indicated proteins in MDA-MB-468 (A, B) and HCC1937 (C-E) cells treated with PTX, SM#9 or SMI#9 + PTX at the indicated nanomolar concentrations. E Cyclin B1 analysis in MG132 treated HCC1937 cells. B, D Protein levels were normalized to β-actin using Image J software

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BMC Cancer

ISSN: 1471-2407

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