Table 3 Multivariate cox regression analyses of prognostic factors associated with overall survival and progression-free survival in 99 patients with hypopharyngeal squamous cell carcinoma

Tumor site

 Pyriform sinus

Reference

0.160

Reference

0.051

 Not pyriform sinus

0.481 (0.173–1.336)

0.394 (0.154–1.004)

cT stage

 T1–2

Reference

0.772

Reference

0.239

 T3–4

1.149 (0.450–2.934)

1.686 (0.707–4.019)

Pathological stage

 I + II + III

Reference

0.227

Reference

0.038

 IV

2.174 (0.617–7.662)

8.339 (1.119–62.132)

Lymphovascular invasion

 No

Reference

0.036

Reference

0.020

 Yes

3.464 (1.084–11.075)

3.367 (1.213–9.345)

c-Jun expression

 Low

Reference

0.035

Reference

0.476

 High

3.313 (1.089–10.081)

1.374 (0.573–3.295)