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Fig. 1 | BMC Cancer

Fig. 1

From: EVI1 expression in early-stage breast cancer patients treated with neoadjuvant chemotherapy

Fig. 1

Distribution of EVI1 protein expression in breast cancer: Panels A-F show exemplary immunohistochemical micrographs across a range of EVI1 H-score values (entire cohort N = 993): A H-score 291 B H-score 205, C H-score 154, D H-score 105, E H-score 60 and F H-score 3. EVI1 expression levels were determined using H-score defined as a cumulative measurement of staining intensity and percentage of positive cells. G Bar chart plots of EVI1 dichotomized expression within breast cancer subtypes. EVI1 H-score was categorized based on the median cut-off into low (≤ 112.16 score) or high (≥ 112.17 score). Note, 882/993 patients with available BC subtype information were included in this analysis. Abbreviations: HR, hormone receptor; HER2, human epidermal growth factor receptor 2; TNBC, triple-negative breast cancer; BC, breast cancer

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