Fig. 1

The mRNA expression patterns of OAS1, OAS2, OAS3, and OASL in different types of human cancer. A Results of Oncomine database analysis. Red colored squares at the left column indicated higher expression (tumor vs. normal), while blue colored squares at the right column indicated lower expression (tumor vs. normal). The numbers in the red squares represented evidence amounts of higher expression. The numbers in blue squares indicated evidence amount of lower expression. Color shades indicated expression levels. White squares referred to no evidence or no change in expression (Fold change > 2, P < 0.0001). B Expression levels of OAS gene family in different types of human tumors derived from TCGA database and determined by TIMER. BLCA was marked by a red square in each subpanel (* P < 0.05, ** P < 0.01, *** P < 0.001). C Expressions of the four OAS genes in various cancers from GEPIA. Color depth represented expression level. BLCA was marked by a red square. T: tumor. N: normal. D Results of GEPIA database analysis. Red fonts represented significantly high expression; green fonts meant low expression; black fonts denoted undifferentially expressed OAS genes in these cancers. Abbreviations of tumor names: ACC, adrenocortical carcinoma. BLCA, bladder cancer. BRCA, breast invasive carcinoma. CESC, cervical squamous cell carcinoma and endocervical adenocarcinoma. CHOL, cholangio carcinoma. COAD, colon adenocarcinoma. DLBC, lymphoid neoplasm diffuse large B-cell lymphoma. ESCA, esophageal carcinoma. GBM, glioblastoma multiforme. HNSC, head and neck squamous cell carcinoma. KICH, kidney chromophobe. KIRC, kidney renal clear cell carcinoma. KIRP, kidney renal papillary cell carcinoma. LAML, acute myeloid leukemia. LGG, brain lower grade glioma. LIHC, liver hepatocellular carcinoma. LUAD, lung adenocarcinoma. LUSC, lung squamous cell carcinoma. OV, ovarian serous cystadenocarcinoma. PAAD, pancreatic adenocarcinoma. PCPG, pheochromocytoma and paraganglioma. PRAD, prostate adenocarcinoma. READ, rectum adenocarcinoma. SARC, sarcoma. SKCM, skin cutaneous melanoma. STAD, stomach adenocarcinoma. TGCT, testicular germ cell tumor. THCA, thyroid carcinoma. THYM, thymoma. UCEC, uterine corpus endometrial carcinoma. UCS, uterine carcinosarcoma. UVM, uveal melanoma