Table 3 Hazard ratios (HRs) for the association of TG, FBG or HDL-C with CRC risk

TG (continuous, per SD)

593/1145910

1.05(1.00,1.11)

0.051

1.05(0.99,1.10)

0.089

Quartiles of TG

 Q1 (≤0.90)

109/294585

Ref.

Ref.

 Q2 (0.90 ~ 1.27)

142/281968

1.36(1.06,1.75)

0.016

1.30(1.01,1.67)

0.041

 Q3 (1.27 ~ 1.93)

179/284244

1.70(1.34,2.15)

< 0.001

1.58(1.24,2.01)

< 0.001

 Q4 (≥1.93)

163/285114

1.54(1.21,1.96)

0.017

1.45(1.13,1.85)

0.003

 pfor trend

< 0.001

0.002

FBG (continuous, per SD)

593/1145910

1.06(1.02,1.10)

0.006

1.05(1.01,1.09)

0.009

Definition of diabetes^a

 None (<  6.1 mmol/L)

144/289661

Ref.

Ref.

 IFG or IGT (6.1 ~ 7.0)

128/290728

1.23(0.93,1.63)

0.141

1.09(0.83,1.44)

0.538

 Diabetes (≥ 7.0 mmol/l)

188/280042

1.59(1.24,2.05)

< 0.001

1.33(1.03,1.72)

0.029

 pfor trend

< 0.001

0.086

HDL-C (continuous, per SD)

593/1145910

1.21(0.99,1.47)

0.059

1.09(0.89,1.32)

0.402

Quartiles of HDL-C

 Q1 (≤1.28)

162/290143

Ref.

Ref.

 Q2 (1.28 ~ 1.51)

126/293293

0.77(0.61,0.97)

0.027

0.77(0.61,0.97)

0.028

 Q3 (1.51 ~ 1.77)

131/285994

0.82(0.65,1.03)

0.093

0.82(0.65,1.03)

0.088

 Q4 (≥1.77)

174/276480

1.12(0.91,1.39)

0.288

1.02(0.82,1.27)

0.856

 pfor trend

0.003

0.031