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Table 4 Univariable and Multivariable analyses of covariable associated with OS

From: Effect of thoracic radiotherapy dose on the prognosis of advanced lung adenocarcinoma harboring EGFR mutations

Variable

Univariate analysis

Multivariate analysis

HR (95% CI)

P

HR (95% CI)

P

Sex

 Male VS Female

0.875 (0.559 to 1.371)

0.563

  

Age

  ≥ 60 VS < 60

1.086 (0.678 to 1.739)

0.733

  

Tobacco smoking

 yes VS no

0.651 (0.358 to 1.186)

0.104

0.785 (0.494 to 1.247)

0.305

EGFR mutation, n (%)

 19 VS 21

0.695 (0.434 to 1.113)

0.130

0.721 (0.421 to 1.233)

0.232

Number of radiotherapy sites

 1 VS 2–6

0.617 (0.377 to 1.010)

0.086

0.743 (0.413 to 1.335)

0.321

The Site of radiotherapy

 Brain yes VS no

0.778 (0.494 to 1.225)

0.279

  

 Bone yes VS no

0.751 (0.479 to 1.175)

0.199

  

Dose, Gy

 

0.011

  

  < 50

0.457 (0.253 to 0.826)

0.009

  

  ≥ 50, < 60

1.247 (0.788 to 1.974)

0.528

  

  ≥ 60

0.628 (0.399 to 0.987)

0.011

0.606 (0.382 to 0.961)

0.033

Radiotherapy targeting synchronization

 yes VS no

0.743 (0.439 to 1.259)

0.308

0.758 (0.423 to 1.357)

0.351

  1. Abbreviations: OS Overall survival