Fig. 1

NR1H4 was overexpressed in ccRCC. A NR1H4 expression levels in different tumor types from TCGA dataset were determined by TIMER2.0 database. B NR1H4 expression levels in different tumor types from TCGA and GTEx dataset were determined by GEPIA database. C NR1H4 mRNA expression level in KIRC, KIRP and PAAD. D NR1H4 mRNA and protein expression in ccRCC by the UALCAN database. E Expression of NR1H4 in ccRCC and normal tissues in GEO database, including GSE167093 (n = 858), GSE46699 (n = 130) and GSE40435 (n = 202). F Expression analysis of NR1H4 based on different variables including patient age, patient gender, individual cancer stages, tumor grade and nodal metastasis status. NR1H4, Nuclear receptor subfamily 1 group H member 4; ccRCC, clear cell renal cell carcinoma; TIMER, Tumor Immune Estimation Resource; KIRC, kidney renal clear cell carcinoma; KIRP, kidney renal papillary cell carcinoma; PAAD, pancreatic adenocarcinoma; GEO, Gene Expression Omnibus; TCGA, The Cancer Genome Atlas; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001