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Table 1 Baseline characteristics of DLBCL patients completed 3 cycles of (R)-CHOP chemotherapy

From: Study on influencing factors of anthracycline-induced subclinical cardiotoxicity in DLBCL patients administered (R)-CHOP

 

All patients

No-AISC

AISC

P-value

N = 70

N = 44

N = 26

Age (year)

55.47 ± 13.63

55.50 ± 14.86

55.42 ± 11.54

0.982

Male/female (n)

33/37

20/24

13/13

0.713

BMI (kg/m2)

22.85 ± 3.31

22.12 ± 3.20

24.10 ± 3.18

0.014

Smoking(%)

17 (24.29)

7 (15.91)

10 (38.46)

0.033

GLS (-%)

20.04 ± 2.24

19.73 ± 2.29

20.58 ± 2.08

0.125

E (cm/s)

67.79 ± 13.01

66.01 ± 11.47

70.81 ± 15.01

0.137

e’(cm/s)

7.27 ± 2.03

6.92 ± 1.98

7.85 ± 2.02

0.067

LDL-C (mmol/L)

2.56 ± 0.77

2.42 ± 0.68

2.80 ± 0.85

0.046

NT-proBNP (ng/L)

54.00 (31.00, 127.00)

70.50 (32.25, 132.25)

41.50 (24.25, 76.50)

0.070

TC (mmol/L)

4.19 ± 0.93

4.07 ± 0.86

4.39 ± 1.02

0.168

TG (mmol/L)

1.36 (1.02, 1.68)

1.25 (0.91, 1.55)

1.54 (1.27, 1.92)

0.009

  1. Values are expressed as mean ± standard deviation, n (%), or median (Q1-Q3). Bold values indicate statistical significance (P < 0.05)
  2. AISC Anthracycline-induced subclinical cardiotoxicity, BMI Body mass index, DLBCL Diffuse large-B cell lymphoma, E mitral inflow E velocity, e’ mitral e’ velocity, GLS Global longitudinal peak systolic strain, LDL-C Low-density lipoprotein cholesterol, NT-proBNP N terminal-pro brain natriuretic peptide, TC Total triglyceride, TG Total cholesterol