Fig. 3

Effect of AZD0156 and SN38 on cell cycle progression in CRC cell lines. Cell cycle analysis by flow cytometry in CRC cells treated with AZD0156 50 nM or 100 nM and SN38 10 nM alone or in combination at 24 h. Data are presented as % cells in G1 Phase, S Phase, and G2/M Phase for each cell line evaluated. Experiments performed with 3 replicates. * = p ≤ 0.05, ** = p ≤ 0.01, *** = p ≤ 0.001, **** = p ≤ 0.0001