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Table 6 The main toxicity attributed to intracranial radiotherapy

From: Real-world analysis of different intracranial radiation therapies in non-small cell lung cancer patients with 1–4 brain metastases

Toxicity

Total (N = 156)

LINAC-SRS (N = 77)

WBRT (N = 44)

WBRT + RTB (N = 35)

P

Nervous system (encephaledema, memory and cognitive decline N (%)

32 (20.5)

16 (20.77)

8 (18.18)a

8 (22.86)a

0.108

Cutaneous radiation reaction N (%)

48 (30.8)

28 (36.36)

6 (13.64)

14 (40.00)

0.156

Systemic toxicityb N (%)

6 (3.85)

3 (3.90)

2 (4.55)

1 (2.86)

0.738

  1. aThere was one case of grade 2 toxicity
  2. bThe most common systemic toxicities were digestive system side-effect and myelosuppression. LINAC-SRS stereotactic radiotherapy using linear accelerators, WBRT whole-brain radiotherapy, WBRT + RTB whole-brain radiotherapy plus radiotherapy boost