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Table 3 Multivariate analysis of OS

From: Real-world analysis of different intracranial radiation therapies in non-small cell lung cancer patients with 1–4 brain metastases

Parameter

median OS (m)

HR

95%CI

P

Sex

   

0.111

 Female

-

1.000

  

 Male

33.3

1.976

0.856–4.558

 

Smoking history

   

0.696

 N0

39.8

1.000

  

 Yes

27.9

1.154

0.562–2.369

 

Tumor histology

   

0.175

 SCC

21.3

1.000

  

 Adenocarcinoma

36.3

0.612

0.301–1.244

 

Thoracic operation

   

0.966

 Yes

39.8

1.000

  

 No

28.9

1.013

0.562–1.825

 

Neurologic symptoms

   

0.002

 No

76.4

1.000

  

 Yes

21.3

2.462

1.401–4.326

 

BMsize, Dmax(cm)

   

0.189

  ≤ 3

36.4

1.000

  

  > 3

18.4

1.555

0.805–3.004

 

EMs

   

0.581

 No

36.4

1.000

  

 Yes

28.9

1.190

0.642–2.207

 

RPA class

   

0.010

 1

76.4

1.000

  

 2

24.0

2.918

1.294–6.579

 
  1. Abbreviations: BMs brain metastases, EMs extracranial metastases, GPA graded prognostic assessment, HR hazard ratio, LINAC-SRS stereotactic radiotherapy using linear accelerators, KPS Kanofsky Performance Scale, RPA recursive partitioning analysis, SCC squamous cell carcinoma, TT targeted therapy, WBRT whole-brain radiotherapy, WBRT + RTB whole-brain radiotherapy plus radiotherapy boost