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Table 2 TCGA cancer types and corresponding pan-cancer organ systems

From: Pan-cancer analysis of genomic and transcriptomic data reveals the prognostic relevance of human proteasome genes in different cancer types

Disease name and pan-organ system

Cohort

RNA-seq dataa

Survival analysisb

cBioPortalc

KM plotterd

  

Cancer tissue

Normal tissue

   

Central nervous system (CNS)

  Glioblastoma multiforme

GBM

166

5

167

592

 

  Brain lower grade glioma

LGG

530

0

528

514

 

Endocrine

  Adrenocortical carcinoma

ACC

79

0

79

92

 

  Thyroid carcinoma

THCA

496

58

510

500

 

Gastrointestinal

  Cholangiocarcinoma

CHOL

36

9

36

36

 

  Colon adenocarcinoma

COAD

191

0

469

  

  Esophageal carcinoma

ESCAe

185

11

162

182

 

  Liver hepatocellular carcinoma

LIHC

147

50

374

372

364

  Pancreatic adenocarcinoma

PAAD

56

0

178

184

 

  Rectum adenocarcinoma

READ

72

0

166

  

  Colorectal adenocarcinoma/Rectum adenocarcinoma

COADREADf

 

0

 

594

 

  Stomach adenocarcinoma

STAD

415

35

375

440

875

Gynecologic

  Breast invasive carcinoma

BRCA

1026

108

1103

1084

1879

  Cervical and endocervical cancers

CESC

159

0

306

297

 

  Ovarian serous cystadenocarcinoma

OV

265

0

379

585

1656

  Uterine corpus endometrial carcinoma

UCEC

369

0

548

529

 

Head and neck

  Head and neck squamous cell carcinoma

HNSC

425

42

502

523

 

Hematologic and lymphatic malignancies

  Lymphoid neoplasm diffuse large B-cell lymphoma

DLBC

48

0

48

48

 

  Acute myeloid leukemia

LAML

173

0

151

200

 

  Thymoma

THYM

120

0

119

123

 

Melanocytic

  Skin cutaneous melanoma

SKCM

472

0

471

448

 

  Uveal melanoma

UVM

80

0

80

80

 

Neural crest-derived

  Pheochromocytoma and paraganglioma

PCPG

184

3

183

178

 

Soft tissue

  Sarcoma

SARC

105

0

263

255

 

  Uterine carcinosarcoma

UCS

57

0

56

57

 

Thoracic

  Lung adenocarcinoma

LUAD

490

58

526

566

1925

  Lung squamous cell carcinoma

LUSC

482

50

501

487

  Mesothelioma

MESO

87

0

86

87

 

Urologic

  Bladder urothelial carcinoma

BLCA

223

19

411

411

 

  Kidney chromophobe

KICH

66

25

65

65

 

  Kidney renal clear cell carcinoma

KIRC

507

72

535

512

 

  Kidney renal papillary cell carcinoma

KIRP

161

30

289

283

 

  Prostate adenocarcinoma

PRAD

498

52

499

494

 

  Testicular germ cell tumors

TGCT

156

0

139

149

 

  Total

 

8526

627

10,304

10,967

6699

  1. a UNC RNASeqV2 level 3 expression (normalized RSEM) data were retrieved from Broad GDAC Firehose (https://gdac.broadinstitute.org/)
  2. b Survival analysis was performed using the dataset https://gdc.cancer.gov/about-data/publications/PanCan-Clinical-2018
  3. c Mutational profiling data (mutated genes, CNA genes, and fusion genes) was retrieved from cBioPortal for Cancer Genomics, http://www.cbioportal.org/study/summary?id=laml_tcga_pan_can_atlas_2018%2Cacc_tcga_pan_can_atlas_2018%2Cblca_tcga_pan_can_atlas_2018%2Clgg_tcga_pan_can_atlas_2018%2Cbrca_tcga_pan_can_atlas_2018%2Ccesc_tcga_pan_can_atlas_2018%2Cchol_tcga_pan_can_atlas_2018%2Ccoadread_tcga_pan_can_atlas_2018%2Cdlbc_tcga_pan_can_atlas_2018%2Cesca_tcga_pan_can_atlas_2018%2Cgbm_tcga_pan_can_atlas_2018%2Chnsc_tcga_pan_can_atlas_2018%2Ckich_tcga_pan_can_atlas_2018%2Ckirc_tcga_pan_can_atlas_2018%2Ckirp_tcga_pan_can_atlas_2018%2Clihc_tcga_pan_can_atlas_2018%2Cluad_tcga_pan_can_atlas_2018%2Clusc_tcga_pan_can_atlas_2018%2Cmeso_tcga_pan_can_atlas_2018%2Cov_tcga_pan_can_atlas_2018%2Cpaad_tcga_pan_can_atlas_2018%2Cpcpg_tcga_pan_can_atlas_2018%2Cprad_tcga_pan_can_atlas_2018%2Csarc_tcga_pan_can_atlas_2018%2Cskcm_tcga_pan_can_atlas_2018%2Cstad_tcga_pan_can_atlas_2018%2Ctgct_tcga_pan_can_atlas_2018%2Cthym_tcga_pan_can_atlas_2018%2Cthca_tcga_pan_can_atlas_2018%2Cucs_tcga_pan_can_atlas_2018%2Cucec_tcga_pan_can_atlas_2018%2Cuvm_tcga_pan_can_atlas_2018
  4. d Survival analysis using KM plotter, https://kmplot.com/analysis/
  5. e Esophageal adenocarcinoma and Esophageal squamous carcinoma was merged into one as Esophageal carcinoma
  6. f COAD and READ was merged in cBioPortal dataset
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BMC Cancer

ISSN: 1471-2407

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