Table 3 Correlation between expression of TROP2 and phenotype and other proteins (p53 and Ki-67) in two primary TNBC cohorts
From: Trophoblast cell-surface antigen 2 (TROP2) expression in triple-negative breast cancer
Factors | Total (%) | TROP2 expression | p-value | |
|---|---|---|---|---|
Cohort 1 | Â | Low (%) | High (%) | Â |
 Phenotype |  |  |  | .004 |
  Basal | 345 (49.3) | 170 (55.4) | 175 (44.5) |  |
  Non-basal | 355 (50.7) | 137 (44.6) | 218 (55.5) |  |
 p53 |  |  |  | .417 |
   < 10 | 324 (45.3) | 148 (47.3) | 176 (43.8) |  |
  10–32 | 64 (9.0) | 22 (7.0) | 42 (10.4) |  |
  33–65 | 35 (4.9) | 16 (5.1) | 19 (4.7) |  |
   ≥ 66 | 292 (40.8) | 127 (40.6) | 165 (41.0) |  |
 Ki-67 (%) |  |  |  | .711 |
   < 10 | 39 (6.5) | 14 (5.7) | 25 (7.0) |  |
  10–19 | 47 (7.8) | 21 (8.6) | 26 (7.3) |  |
   ≥ 20 | 514 (85.7) | 209 (85.7) | 305 (85.7) |  |
Cohort 2 | Â | Low (%) | High (%) | Â |
 Phenotype |  |  |  | .675 |
  Basal | 17 (26.6) | 6 (30.0) | 11 (25.0) |  |
  Non-basal | 47 (73.4) | 14 (70.0) | 33 (75.0) |  |
 p53 |  |  |  | .428 |
   < 10 | 29 (45.3) | 10 (50.0) | 19 (43.2) |  |
  10–32 | 1 (1.6) | 0 (0.0) | 1 (2.3) |  |
  33–65 | 3 (4.7) | 2 (10.0) | 1 (2.3) |  |
   ≥ 66 | 31 (48.4) | 8 (40.0) | 23 (52.3) |  |
 Ki-67 (%) |  |  |  | .555 |
   < 10 | 12 (18.8) | 5 (25.0) | 7 (15.9) |  |
  10–19 | 2 (3.1) | 1 (5.0) | 1 (2.3) |  |
   ≥ 20 | 50 (78.1) | 14 (70.0) | 36 (81.8) |  |