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Table 2 Univariate and multivariate analyses of prognostic factors for overall survival in patients with pancreatic cancer

From: Modified geriatric nutritional risk index in patients with pancreatic cancer: a propensity score-matched analysis

  Univariate analysis Multivariate analysis
Variables HR 95% CI P-value HR 95% CI P
Age (≥ 70 vs < 70), years 0.701 0.392–1.253 0.231    
Sex (male vs. female) 2.569 1.360–4.851 0.004 2.499 1.288–4.849 0.007
BMI (< 22 kg/m2 vs ≥ 22 kg/m2) 1.384 0.754–2.541 0.295    
Tumor size (≥ 20.0 mm vs < 20.0 mm) 2.079 0.999–4.327 0.050    
Histological grading for tumor (G2a or G3b vs G1c) 1.564 0.872–2.807 0.134    
Lymph node metastasis (present vs absent) 3.650 1.619–8.228 0.002 3.953 1.723–9.066 0.001
Residual tumor (present vs absent) 2.017 0.721–5.642 0.181    
ASA-PS (3 vs 1 or 2) 2.818 1.436–5.532 0.003 2.187 1.069–4.476 0.032
Preoperative CA19-9 (≥ 274.9 U/mL vs < 274.9 U/mL) 1.425 0.687–2.957 0.342    
Neoadjuvant chemotherapy (present vs. absent) 1.164 0.416–3.260 0.773    
Adjuvant chemotherapy (present vs. absent) 0.784 0.435–1.141 0.419    
PNI (high: ≥ 47.7 vs low: < 477) 1.163 0.647–2.092 0.613    
mGNRI (high: ≥ 85.3 vs low: < 85.3) 2.060 1.143–3.713 0.016 2.359 1.291–4.311 0.005
  1. aG2: moderately-differentiated
  2. bG3: poor-differentiated
  3. cG1: well-differentiated
  4. HR Hazard ratio, CI Confidence interval, BMI Body mass index, ASA-PS American Society of Anesthesiologists physical status, CA19-9 Carbohydrate antigen 19–9, mGNRI Modified geriatric nutritional risk index