Modified geriatric nutritional risk index in patients with pancreatic cancer: a propensity score-matched analysis

BMC Cancer

Table 2 Univariate and multivariate analyses of prognostic factors for overall survival in patients with pancreatic cancer

	Univariate analysis			Multivariate analysis
Variables	HR	95% CI	P-value	HR	95% CI	P
Age (≥ 70 vs < 70), years	0.701	0.392–1.253	0.231
Sex (male vs. female)	2.569	1.360–4.851	0.004	2.499	1.288–4.849	0.007
BMI (< 22 kg/m² vs ≥ 22 kg/m²)	1.384	0.754–2.541	0.295
Tumor size (≥ 20.0 mm vs < 20.0 mm)	2.079	0.999–4.327	0.050
Histological grading for tumor (G2^a or G3^b vs G1^c)	1.564	0.872–2.807	0.134
Lymph node metastasis (present vs absent)	3.650	1.619–8.228	0.002	3.953	1.723–9.066	0.001
Residual tumor (present vs absent)	2.017	0.721–5.642	0.181
ASA-PS (3 vs 1 or 2)	2.818	1.436–5.532	0.003	2.187	1.069–4.476	0.032
Preoperative CA19-9 (≥ 274.9 U/mL vs < 274.9 U/mL)	1.425	0.687–2.957	0.342
Neoadjuvant chemotherapy (present vs. absent)	1.164	0.416–3.260	0.773
Adjuvant chemotherapy (present vs. absent)	0.784	0.435–1.141	0.419
PNI (high: ≥ 47.7 vs low: < 477)	1.163	0.647–2.092	0.613
mGNRI (high: ≥ 85.3 vs low: < 85.3)	2.060	1.143–3.713	0.016	2.359	1.291–4.311	0.005

^aG2: moderately-differentiated
^bG3: poor-differentiated
^cG1: well-differentiated
HR Hazard ratio, CI Confidence interval, BMI Body mass index, ASA-PS American Society of Anesthesiologists physical status, CA19-9 Carbohydrate antigen 19–9, mGNRI Modified geriatric nutritional risk index

ISSN: 1471-2407