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Table 2 Patient demographic profile and baseline disease characteristics

From: Effects of topical timolol for the prevention of radiation-induced dermatitis in breast cancer: a pilot triple-blind, placebo-controlled trial

Parameters

Groups

P-Value

Timolol

Placebo

 

(N = 32)

(N = 32)

 

Age, Mean (SD)

53.8 (11.0)

54.8 (12.4)

0.735

BMI, kg/m2

23.1 (2.9)

22.8 (3.3)

0.551

Coexisting conditions, N (%)

 Hypertension

4 (12.5)

3 (9.4

0.457

 Diabetes mellitus

5 (15.6)

7 (21.9)

 

Dyslipidemia

6 (18.7)

7 (21.9)

 

 Skin phototype, N (%)

 Type 1

0 (0.0)

0 (0.0)

0.143

 Type 2

0 (0.0)

3 (9.4)

 

 Type 3

19 (59.4)

21 (65.6)

 

 Type 4

12 (37.5)

6 (18.7)

 

 Type 5

1 (3.1)

2 (6.3)

 

Laterality, N (%)

 Right

10 (31.0)

11 12 (34.0)

0.224

 Left

21(66.0)

17 (54.0)

 

 Both

1 (3.0)

4 (12.0)

 

Type of breast surgery, N (%)

 BCS

28 (87.5)

29 (90.6)

0.782

 MRM

4 (12.5)

3 (9.4)

 

History of chemotherapy, N (%)

 Yes

14 (43.7)

13 (40.6)

0.800

Smoking status, N (%)

 Yes

0 (0.0)

1 (3.1)

0.332

Marital status, N (%)

 Single

2 (6.3)

2 (6.3)

1.000

 Married

30 (93.7)

30 (93.7)

 

Her2 status

 Positive

11(34.4)

14(43.7)

 

 Hormone receptor status

  

0.442

 ER+/PR+

19 (59.4)

22 (68.7)

0.736

 ER+/PR−

4 (12.5)

3 (9.4)

 

 ER−/PR−

9 (28.1)

7 (21.9)

 
  1. N Number, SD Standard deviation, BCS Breast-conserving surgery, MRM Modified radical mastectomy, HER2 Human epidermal growth factor receptor 2, ER Estrogen receptor, PR Progesterone receptor. Independent-Samples T Test and Chi-squared test were used to compare these values