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Table 1 Acute radiation dermatitis corresponding to the RTOG/EORTC and CTCAE scoring criteria

From: Effects of topical timolol for the prevention of radiation-induced dermatitis in breast cancer: a pilot triple-blind, placebo-controlled trial

 

Grade

0

1

2

3

4

5

RTOG/EORTC

No skin rending, ulceration, inflammation or damage

Follicular, faint or dull erythema or dry desquamation

Moderate to brisk erythema, patchy moist desquamation mostly confined to skin folds and creases, moderate edema

Confluent, moist desquamation other than skin

Folds (≤ 1.5 cm diameter), pitting edema

ulceration of full thickness dermis or skin necrosis, spontaneous bleeding from the involved site

Death

CTCAE (v5.0)

No dermatitis

Combined area of ulcers < 1 cm, faint erythema or dry desquamation

Combined area of ulcers 1—2 cm; moderate to brisk erythema, patchy moist desquamation, moderate edema

Combined area of ulcers > 2 cm; full-thickness

skin loss involving damage to subcutaneous tissue that may extend down to

fascia

life-threatening consequences, skin necrosis or ulceration of full thickness dermis, spontaneous bleeding from involved site, skin graft indicated

  1. RTOG/EORTC Radiation therapy oncology group and the european organization for research and treatment of cancer; CTCAE (v5.0) Common terminology criteria for adverse event (version 5)