From: The impact of age on rectal cancer treatment, complications and survival
Factor | Unadjusted hazard ratio (95% CI) | p value | Adjusted hazard ratio (95% CI) | p value |
---|---|---|---|---|
Age (years) | ||||
 <65 | 1 (reference) |  | 1 (reference) |  |
 65 - 79 | 2.25 (0.95 to 5.32) | 0.065 | 1.82 (0.71 to 4.67) | 0.22 |
 80 + | 2.92 (0.86 to 9.77) | 0.081 | 1.58 (0.42 to 5.93) | 0.50 |
Female sex | 1.24 (0.60 to 2.56) | 0.57 | 1.17 (0.60 to 2.29) | 0.65 |
Calendar year | ||||
 1980-1989 | 1 (reference) |  | 1 (reference) |  |
 1990-1999 | 1.63 (0.60 to 4.43) | 0.34 | 0.95 (0.35 to 2.60) | 0.92 |
 2000-2009 | 1.01 (0.36 to 2.87) | 0.98 | 0.74 (0.27 to 2.05) | 0.57 |
 2010-2016 | 0.52 (0.13 to 2.13) | 0.36 | 0.42 (0.13 to 1.34) | 0.14 |
Charlson Index | ||||
 0 | 1 (reference) |  | 1 (reference) |  |
 1 | 2.97 (1.14 to 7.74) | 0.026 | 2.06 (0.83 to 5.12) | 0.12 |
 2 | 4.09 (1.71 to 9.78) | 0.002 | 1.78 (0.66 to 4.82) | 0.26 |
 3 + | 6.08 (1.91 to 19.31) | 0.002 | 4.90 (1.47 to 16.30) | 0.010 |
ASAÂ score | ||||
 1-2 | 1 (reference) |  | 1 (reference) |  |
 3-4 | 3.43 (1.70 to 6.91) | 0.001 | 2.37 (1.11 to 5.05) | 0.026 |
Emergency surgery | 7.19 (2.63 to 19.64) | <0.001 | 4.88 (1.23 to 19.41) | 0.025 |
TNM-stage | ||||
 I-II | 1 (reference) |  | 1 (reference) |  |
 III | 3.72 (1.67 to 8.29) | 0.001 | 2.70 (1.32 to 5.52) | 0.007 |
Type of resection | ||||
 R0 - resection | 1 (reference) |  | 1 (reference) |  |
 R0 - resection with perforation | 2.92 (0.78 to 10.94) | 0.11 | 1.20 (0.23 to 6.21) | 0.83 |
 R1 - resection | 5.98 (2.26 to 15.84) | <0.001 | 2.03 (0.65 to 6.37) | 0.23 |