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Table 4 Characteristics of 431 patients with stages I-III rectal cancer that underwent a major resection with curative intent in 1980-2016, grouped according to age

From: The impact of age on rectal cancer treatment, complications and survival

Characteristic

Total n (%)

Age <65 years, n (%)

Age 65-79 years, n (%)

Age 80+ years, n (%)

P-value

Proportion of total

431/666 (65)

126/193 (65)

237/328 (72)

68/144 (47%)

 

Sex

    

0.29 a

 Females

159 (37)

46 (37)

81 (34)

32 (47)

 

 Males

272 (63)

80 (63)

156 (65)

36 (53)

 

Calendar-year (row %)

    

0.50 b

 1980-1989

82 (19)

23 (28)

49 (60)

10 (12)

 

 1990-1999

116 (27)

31 (27)

71 (62)

14 (12)

 

 2000-2009

119 (28)

38 (32)

60 (50)

21 (18)

 

 2010-2016

114 (26)

34 (30)

57 (50)

23 (20)

 

Charlson Comorbidity Index 

    

0.001 b

 0

350 (81)

114 (90)

187 (79)

49 (72)

 

 1

35 (8)

7 (6)

22 (9)

6 (9)

 

 2 +

46 (11)

5 (4)

28 (12)

13 (19)

 

ASA score

    

<0.001 b

 1-2

291 (68)

108 (86)

157 (66)

26 (38)

 

 3

138 (32)

18 (14)

78 (33)

42 (62)

 

 4-5

2 (0.5)

0

2 (1)

0

 

Localization in rectum

    

0.25 b

 Proximal

153 (36)

51 (40)

79 (33)

23 (34)

 

 Middle

178 (41)

50 (40)

99 (42)

29 (43)

 

 Distal

100 (23)

25 (20)

59 (25)

16 (24)

 

Stage (TNM)

    

0.16 b

 I

119 (28)

38 (30)

66 (28)

15 (22)

 

 II

173 (40)

49 (39)

99 (42)

25 (37)

 

 III

139 (32)

39 (31)

72 (30)

28 (41)

 

Radiochemotherapy

    

0.12 c

 No

345 (80)

96 (76)

190 (80)

59 (87)

 

 Preoperatively

71 (16)

23 (18)

39 (16)

9 (13)

 

 Postoperatively

14 (3)

7 (6)

7 (3)

0

 

Both pre- and postoperatively

1 (0.2)

0

1 (0.4)

0

 

Treatment

    

<0.001 c

 AR

276 (64)

89 (71)

155 (65)

32 (47)

 

 APR

104 (24)

30 (24)

62 (26)

12 (18)

 

 Hartmann’s procedure

48 (11)

7 (6)

18 (8)

23 (34)

 

 Proctocolectomy

3 (1)

0

2 (1)

1 (1)

 

Surgery

    

0.33 a

 Elective surgery

421 (98)

125 (99)

230 (97)

66 (97)

 

 Emergency surgery

10 (2)

1 (1)

7 (3)

2 (3)

 

R stage

    

0.42 b

 R0

405 (94)

121 (96)

222 (94)

62 (91)

 

 R0 with perforation

14 (3)

3 (2)

7 (3)

4 (6)

 

 R1

12 (3)

2 (2)

8 (2)

2 (3)

 
  1. AR anterior resection, APR abdominoperineal resection
  2. a Cochran-Armitage exact trend test
  3. b Ordinal logistic regression with age group as a covariate
  4. c Multinomial logistic regression with age group as a covariate