From: The impact of age on rectal cancer treatment, complications and survival
Characteristic | Total n (%) | Age <65 years, n (%) | Age 65-79 years, n (%) | Age 80+ years, n (%) | P-value |
---|---|---|---|---|---|
Proportion of total | 431/666 (65) | 126/193 (65) | 237/328 (72) | 68/144 (47%) | Â |
Sex | Â | Â | Â | Â | 0.29 a |
 Females | 159 (37) | 46 (37) | 81 (34) | 32 (47) |  |
 Males | 272 (63) | 80 (63) | 156 (65) | 36 (53) |  |
Calendar-year (row %) |  |  |  |  | 0.50 b |
 1980-1989 | 82 (19) | 23 (28) | 49 (60) | 10 (12) |  |
 1990-1999 | 116 (27) | 31 (27) | 71 (62) | 14 (12) |  |
 2000-2009 | 119 (28) | 38 (32) | 60 (50) | 21 (18) |  |
 2010-2016 | 114 (26) | 34 (30) | 57 (50) | 23 (20) |  |
Charlson Comorbidity Index |  |  |  |  | 0.001 b |
 0 | 350 (81) | 114 (90) | 187 (79) | 49 (72) |  |
 1 | 35 (8) | 7 (6) | 22 (9) | 6 (9) |  |
 2 + | 46 (11) | 5 (4) | 28 (12) | 13 (19) |  |
ASA score | Â | Â | Â | Â | <0.001 b |
 1-2 | 291 (68) | 108 (86) | 157 (66) | 26 (38) |  |
 3 | 138 (32) | 18 (14) | 78 (33) | 42 (62) |  |
 4-5 | 2 (0.5) | 0 | 2 (1) | 0 |  |
Localization in rectum |  |  |  |  | 0.25 b |
 Proximal | 153 (36) | 51 (40) | 79 (33) | 23 (34) |  |
 Middle | 178 (41) | 50 (40) | 99 (42) | 29 (43) |  |
 Distal | 100 (23) | 25 (20) | 59 (25) | 16 (24) |  |
Stage (TNM) | Â | Â | Â | Â | 0.16 b |
 I | 119 (28) | 38 (30) | 66 (28) | 15 (22) |  |
 II | 173 (40) | 49 (39) | 99 (42) | 25 (37) |  |
 III | 139 (32) | 39 (31) | 72 (30) | 28 (41) |  |
Radiochemotherapy | Â | Â | Â | Â | 0.12 c |
 No | 345 (80) | 96 (76) | 190 (80) | 59 (87) |  |
 Preoperatively | 71 (16) | 23 (18) | 39 (16) | 9 (13) |  |
 Postoperatively | 14 (3) | 7 (6) | 7 (3) | 0 |  |
Both pre- and postoperatively | 1 (0.2) | 0 | 1 (0.4) | 0 | Â |
Treatment | Â | Â | Â | Â | <0.001 c |
 AR | 276 (64) | 89 (71) | 155 (65) | 32 (47) |  |
 APR | 104 (24) | 30 (24) | 62 (26) | 12 (18) |  |
 Hartmann’s procedure | 48 (11) | 7 (6) | 18 (8) | 23 (34) |  |
 Proctocolectomy | 3 (1) | 0 | 2 (1) | 1 (1) |  |
Surgery | Â | Â | Â | Â | 0.33 a |
 Elective surgery | 421 (98) | 125 (99) | 230 (97) | 66 (97) |  |
 Emergency surgery | 10 (2) | 1 (1) | 7 (3) | 2 (3) |  |
R stage | Â | Â | Â | Â | 0.42 b |
 R0 | 405 (94) | 121 (96) | 222 (94) | 62 (91) |  |
 R0 with perforation | 14 (3) | 3 (2) | 7 (3) | 4 (6) |  |
 R1 | 12 (3) | 2 (2) | 8 (2) | 2 (3) |  |