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Fig. 2 | BMC Cancer

Fig. 2

From: Preoperative serum CA19-9 should be routinely measured in the colorectal patients with preoperative normal serum CEA: a multicenter retrospective cohort study

Fig. 2

Association between preoperative CA19-9 status and recurrence-free survival. (a) overall population. (b) patients with normal preoperative CEA. (c) patients with elevated preoperative CEA. Solid yellow lines are unadjusted hazard ratios, with dashed yellow lines showing 95% confidence intervals derived from restricted cubic spline regressions. Reference lines for no association are indicated by the solid bold lines at a hazard ratio (HR) of 1.0. Dashed blue curves show the fraction of the population with different levels of preoperative CA19-9. Arrows indicate the concentration of preoperative CA19-9 with HR of 1.0. CA19-9, carbohydrate antigen 19–9; CEA, carcinoembryonic antigen; CI, confidence interval; E, number of events; HR, hazard ratio; N, number of patients

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