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Table 1 Baseline clinical characteristics of the study cohort and best response to combination therapy

From: Sintilimab plus docetaxel as second-line therapy of advanced non-small cell lung cancer without targetable mutations: a phase II efficacy and biomarker study

Characteristics

Total, No. (%)

No. of patients

30

Age, years

 Median

56

 Range

48–69

Sex

 Male

22 (73.4)

 Female

8 (26.6)

Smoking history

 Never smoker

14 (46.7)

 Former smoker

16 (53.3)

Histology

 Adenocarcinoma

16 (53.3)

 Squamous carcinoma

14 (46.7)

Eastern Cooperative Oncology Group performance status

 0–1

30 (100)

  ≥ 2

0

Brain metastasis

 Yes

1 (3.3)

 No

29 (96.7)

Stage

 IIIa/IIIb

4 (13.4)

 IV

26 (86.6)

Best response with sintilimab plus docetaxel

 Complete Response

0

 Partial Response

11 (36.7)

 Stable Disease

13 (43.3)

 Progressive Disease

6 (20)

 Objective Response Rate

36.7%