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Table 1 Differential analysis between alveoli/lepidic and acinar/papillary according to the pathological components of the area adjacent pleura and CT manifestation

From: Pathological components and CT imaging analysis of the area adjacent pleura within the pure ground-glass nodules with pleural deformation in invasive lung adenocarcinoma

Variable

Alveoli/Lepidic(n = 54)

Acinar/Papillary(n = 27)

Total(n = 81)

P value

Age Median (25th to 75th percentile) years

58.50(47.50, 64.25)

61.00(51.00, 63.00)

60.00(49.50, 64.00)

0.790

Sex/Male, No. (%)

17(31.48%)

7(25.93%)

24(29.63%)

0.797

Smoking history, No. (%)

4(7.41%)

2(7.41%)

6(7.41%)

1.000

Pathological types, No. (%)

   

 < 0.001

IAC

11(20.37%)

20(74.07%)

31(38.27%)

 

MIA

43(79.63%)

7(25.93%)

50(61.73%)

 

Ki-67, No. (%)

   

0.244

 < 10%

48(94.12%)

20(83.33%)

68(90.67%)

 

 ≥ 10%

3(5.88%)

4(16.67%)

7(9.33%)

 

Absence

3

3

6

 

Distance(mm), median (25th – 75th percentile)

1.50(1.00, 2.00)

0.00(0.00, 0.00)

1.00(0.00, 2.00)

 < 0.001

Depth(mm) median (25th – 75th percentile)

2.00(0.50, 3.25)

6.00(4.00, 10.00)

3.00(1.00, 6.00)

 < 0.001

Tumor location, No. (%)

   

0.247

Right upper lobe

16(29.63%)

15(55.55%)

31(38.27%)

 

Right middle lobe

5(9.26%)

2(7.41%)

7(8.64%)

 

Right lower lobe

12(22.22%)

5(18.52%)

17(20.99%)

 

Left upper lobe

14(25.93%)

3(11.11%)

17(20.99%)

 

Left lower lobe

7(12.96%)

2(7.41%)

9(11.11%)

 

Shape, No. (%)

   

1.000

Irregular

20(37.04%)

10(37.04%)

30(37.04%)

 

Round and oval

34(62.96%)

17(62.96%)

51(62.96%)

 

Lobulation, No. (%)

   

0.098

Absent

19(35.19%)

15(55.56%)

34(41.98%)

 

Presence

35(64.81%)

12(44.44%)

47(58.02%)

 

Vacuole, No. (%)

   

1.000

Absent

40(74.07%)

20(74.07%)

60(74.07%)

 

Presence

14(25.93%)

7(25.93%)

21(25.93%)

 

AirBronchogram, No. (%)

   

0.321

Absent

45(83.33%)

25(92.59%)

70(86.42%)

 

Presence

9(16.67%)

2(7.41%)

11(13.58%)

 

Pleural deformation, No. (%)

   

0.157

Type a

11(20.37%)

7(25.93%)

18(22.22%)

 

Type b

7(12.96%)

3(11.11%)

10(12.35%)

 

Type c

13(24.07%)

3(11.11%)

16(19.75%)

 

Type d

17(31.48%)

14(51.85%)

31(38.27%)

 

Type e

6(11.11%)

0(0.00%)

6(7.40%)

 

CTv (HU)

-634.15(-676.02, -590.10)

-582.94(-652.12, -524.14)

-618.26(-672.59, -577.62)

0.024

MD (mm)

13.75(11.18, 17.93)

18.20(14.30, 23.20)

14.80(11.50, 19.40)

0.001

MVD (mm)

10.30(8.06, 13.38)

15.00(11.00, 17.30)

11.40(8.66, 15.65)

0.002

  1. Distance: The distance between invasive components area and non-interlobar pleura; Depth: Depth is defined as the vertical distance between the point closest to the non-interlobar pleura and the point farthest from the non-interlobar pleura; CTv refers to the CT attenuation value on the maximum axial layer; MD refers to the maximum diameter on the maximum axial layer; MVD refers to the maximum vertical diameter of the maximum diameter on the maximum axial layer