Fig. 1
Expression of pluripotent genes and the correlation with OS in OC. A Immunohistochemical (IHC) staining of OCT4, SOX2, and NANOG expression in clinical tumors. OCT4-, SOX2-, and NANOG- indicate no primary antibody incubation during the staining procedure (original magnification, × 400). B Correlation of each single marker and OCT4high or SOX2high plus other markers with OS in operative patients with OC. Statistical analysis was carried out using SPSS 22.0 (IBM Corp., Armonk, NY, USA). Kaplan–Meier curves were used to evaluate the correlation of highly expressed markers with OS. Comparisons of two groups were made by the log-rank test. *P < 0.05 was considered significant. (C) Correlation of each marker with OS in 213 patients with grade 2 + 3 serous ovarian carcinoma containing Paclitaxel treatment from the dataset of Kaplan–Meier Plotter (https://kmplot.com/analysis/). Kaplan–Meier curves were used to evaluate the correlation of highly expressed markers with OS. Comparisons of two groups were made by the log-rank test. *P < 0.05 was considered significant