NudCD1 as a prognostic marker in colorectal cancer and its role in the upregulation of cellular spindle assembly checkpoint genes and LIS1 pathways

Table 2 The correlation between NudCD1 protein in colorectal cancer tissues with clinicopathological features

Clinicopathological features	n = 100	NudCD1 protein level ( n)		χ2	P
Clinicopathological features	n = 100	high expression(58)	low expression(42)	χ2	P
Sex
Male	67	37	30	0.642	0.423
Female	33	21	12
Age (Years)
< 60	22	9	13	3.382	0.066
≥ 60	78	49	29
Tumor location
Ascending colon( including Cecum)	35	21	14	1.697	0.791
Transverse colon	8	6	2
Descending colon	13	8	5
Sigmoid colon	11	6	5
Rectum	33	17	16
Gross type
Polyp	21	9	12	3.877	0.144
Invasive	38	21	17
Ulcerative	41	28	13
Tumor diameter (cm)
< 3	42	20	22	3.203	0.073
≥ 3	58	38	20
Neurovascular invasion
No invasion	26	11	15	2.673	0.102
Neuro/vascular invasion	74	45	29
Differentiation
High	32	14	18	10.881	0.004
Medium	25	11	14
Low	43	33	10
Primary tumor invasion
T1, T2	31	13	18	4.760	0.029
T3, T4	69	45	24
Lymph metastasis
N0, N1	72	37	35	4.614	0.032
N2, N3	28	21	7
Distant metastasis
M0	91	51	40	1.588	0.208
M1	9	7	2
TNM classification
I, II	63	27	36	13.176	0.000
III, IV	39	31	8

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